Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12582109 | 0.77 | MMP1 (0.41) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL9585304 | 0.75 | MMP1 (0.44) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL7456997 | 0.72 | PPARD (0.35) | TSHRPPARDTP53TDP1MMP1 | |
| SCHEMBL21098034 | 0.69 | PPARD (0.50) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL31728232 | 0.68 | TSHR (0.39) | TSHRTP53TDP1MEN1KMT2A | |
| Diethyl Hydrogen Phosphate SCHEMBL28931794 | 0.67 | TSHR (0.42) | TSHRPPARDTP53TDP1CA12 | |
| SCHEMBL28496040 | 0.66 | MAN1B1 (0.35) | — | |
| Triethyl Phosphate SCHEMBL7162251 | 0.66 | TSHR (0.81) | TSHRPPARDTP53TDP1CA12 | |
| Phosphine SCHEMBL29117334 | 0.66 | — | — | |
| Diethyl Hydrogen Phosphate SCHEMBL16059148 | 0.66 | TSHR (0.61) | TSHRPPARDTP53TDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |