Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17379416 | 0.92 | BUB1 (1.00) | BUB1 | |
| SCHEMBL17372542 | 0.92 | BUB1 (1.00) | BUB1 | |
| SCHEMBL17372550 | 0.92 | BUB1 (1.00) | BUB1 | |
| SCHEMBL17372545 | 0.92 | BUB1 (1.00) | BUB1 | |
| SCHEMBL17372547 | 0.92 | BUB1 (1.00) | BUB1 | |
| SCHEMBL17379414 | 0.92 | BUB1 (1.00) | BUB1 | |
| SCHEMBL18320089 | 0.90 | BUB1 (0.87) | BUB1 | |
| SCHEMBL20212644 | 0.90 | BUB1 (0.87) | BUB1 | |
| SCHEMBL20212674 | 0.88 | BUB1 (1.00) | BUB1 | |
| SCHEMBL20212588 | 0.88 | BUB1 (1.00) | BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10308629-B2 | 1H-pyrrol-3-amines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308629-B2 | 1H-pyrrol-3-amines | PAH, ADCYAP1R1, NPPA | BUB1 1697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.