Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21064390 | 0.77 | — | — | |
| SCHEMBL31553554 | 0.72 | — | — | |
| SCHEMBL11809503 | 0.65 | HMGCR (0.41) | ALDH1A1CYP2C19 | |
| SCHEMBL4742273 | 0.65 | — | — | |
| SCHEMBL26563512 | 0.64 | — | — | |
| SCHEMBL19692684 | 0.63 | — | — | |
| SCHEMBL20558554 | 0.63 | — | — | |
| SCHEMBL19692947 | 0.63 | — | — | |
| SCHEMBL11168529 | 0.61 | TDP1 (0.53) | ALDH1A1CYP2C9HPGDHSD17B10ALOX15 | |
| SCHEMBL503605 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190291045-A1 | 1-Amino-2-Methyl-2-Propanol Derivatives | TPAT IP LLC | 2019-09-26 | — | — | US | disclosed |
| US-10307707-B2 | 1-amino-2-methyl-2-propanol derivatives | TPAT IP LLC | 2019-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10307707-B2 | 1-amino-2-methyl-2-propanol derivatives | PNMT, PKD1, PKD2 | ALDH1A1 2340/4885CYP2C9 4739/4885HPGD 1346/4885 |
| US-20190291045-A1 | 1-Amino-2-Methyl-2-Propanol Derivatives | PNMT, PKD1, PKD2 | ALDH1A1 2340/4885CYP2C9 4739/4885HPGD 1346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.