Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1355525 | 0.84 | HSD17B10 (0.53) | ALDH1A1TSHRUSP2GAAPKM | |
| SCHEMBL12089542 | 0.82 | EIF4A3 (0.47) | LMNAALDH1A1HPGDHSD17B10FABP4 | |
| SCHEMBL15458032 | 0.81 | MCL1 (0.47) | LMNAALDH1A1TSHRUSP2GAA | |
| SCHEMBL5885088 | 0.81 | ALDH1A1 (0.57) | LMNAALDH1A1USP2GAAPKM | |
| SCHEMBL13633350 | 0.81 | MEN1 (0.41) | LMNAALDH1A1TSHRHPGDHSD17B10 | |
| SCHEMBL3925212 | 0.81 | MEN1 (0.41) | LMNAALDH1A1TSHRHPGDHSD17B10 | |
| SCHEMBL31280455 | 0.80 | HSD17B10 (0.43) | LMNAALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL16398486 | 0.80 | HSD17B10 (0.43) | LMNAALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL4282493 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TSHRUSP2GAAPKM | |
| SCHEMBL10174227 | 0.78 | ALDH1A1 (0.56) | LMNAALDH1A1TSHRUSP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE47415-E1 | Pyrimidinecarboxamides as CXCR2 modulators | SYNTRIX BIOSYSTEMS, INC. (US) | 2019-06-04 | — | — | US | disclosed |