Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2106321 | 0.92 | F11 (0.84) | F11KLKB1 | |
| SCHEMBL2107869 | 0.91 | F11 (0.83) | F11KLKB1 | |
| SCHEMBL2105120 | 0.89 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL2105118 | 0.89 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL13524382 | 0.85 | F11 (1.00) | F11 | |
| SCHEMBL2325281 | 0.84 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL2107862 | 0.84 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL2332908 | 0.84 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL2328198 | 0.83 | F11 (1.00) | F11KLKB1 | |
| SCHEMBL2331259 | 0.83 | F11 (1.00) | F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163749-B2 | Six-membered heterocycles useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-04-24 | — | — | US | claimed |
| US-8163749-B2 | Six-membered heterocycles useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-04-24 | — | — | US | disclosed |