Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 11/20 | 0.40 |
| ▸ | CA1 | P00915 | 10/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404267 | 1.00 | THRB (0.56) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL5704658 | 1.00 | THRB (0.56) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL11656430 | 1.00 | THRB (0.56) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL11653580 | 1.00 | THRB (0.56) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL1405391 | 1.00 | THRB (0.56) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL1055310 | 1.00 | THRB (0.56) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL11398170 | 1.00 | THRB (0.56) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL2637496 | 1.00 | THRB (0.56) | THRBCA2CA1MMP1MMP2 | |
| SCHEMBL20657169 | 1.00 | THRB (0.56) | THRBCA2CA1MMP1MMP2 | |
| Ammonia Solution, Strong SCHEMBL10940988 | 0.97 | THRB (0.54) | THRBCA2CA1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158094-B2 | Methods of preparing metal carbides | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2012-04-17 | — | — | US | disclosed |
| US-20100291298-A1 | Methods of Preparing Metal Carbides | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2010-11-18 | — | — | US | disclosed |