Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17993463 | 0.79 | KDM4E (0.65) | KDM4EMAPTHSD17B10LMNAPOLB | |
| SCHEMBL19606247 | 0.73 | KDM4E (0.50) | KDM4EMAPTHSD17B10LMNAPOLB | |
| SCHEMBL861183 | 0.73 | KDM4E (0.57) | KDM4EMAPTHSD17B10LMNAPOLB | |
| SCHEMBL10346630 | 0.72 | KDM4E (0.61) | KDM4EMAPTHSD17B10LMNAPOLB | |
| SCHEMBL37035230 | 0.72 | KDM4E (0.61) | KDM4EMAPTHSD17B10LMNAPOLB | |
| SCHEMBL20821356 | 0.71 | KDM4E (0.59) | KDM4EMAPTHSD17B10LMNAPOLB | |
| SCHEMBL18872983 | 0.70 | KDM4E (0.59) | KDM4EMAPTHSD17B10LMNAPOLB | |
| SCHEMBL31611563 | 0.70 | KDM4E (0.83) | KDM4EMAPTHSD17B10LMNAPOLB | |
| SCHEMBL12145479 | 0.69 | KDM4E (0.61) | KDM4EMAPTHSD17B10LMNAPOLB | |
| SCHEMBL20218957 | 0.68 | KDM4E (0.65) | KDM4EMAPTHSD17B10LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399922-B1 | Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof | UNIVERSAL DISPLAY CORP (US) | 2019-06-26 | — | — | EP | claimed |