SCHEMBL861183

SCHEMBL861183

c1ccc2c(c1)nc1n2c2ccccc2c2nc3ccccc3n21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.57
MAPT P10636 7/20 0.57
HSD17B10 Q99714 5/20 0.57
LMNA P02545 3/20 0.57
TP53 P04637 3/20 0.57
POLB P06746 3/20 0.57
ALDH1A1 P00352 8/20 0.56
HPGD P15428 6/20 0.56
KMT2A Q03164 5/20 0.53
MEN1 O00255 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.49
NPC1 O15118 3/20 0.46
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
TSHR P16473 3/20 0.44
BCL2 P10415 1/20 0.43
GAA P10253 1/20 0.43
HIF1A Q16665 1/20 0.43
CASP1 P29466 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17993463 0.88 KDM4E (0.65) KDM4EMAPTHSD17B10LMNATP53
SCHEMBL37035230 0.81 KDM4E (0.61) KDM4EMAPTHSD17B10LMNATP53
SCHEMBL10346630 0.81 KDM4E (0.61) KDM4EMAPTHSD17B10LMNATP53
SCHEMBL21065258 0.80 KMT2A (0.58) KDM4EMAPTHSD17B10LMNATP53
SCHEMBL20821356 0.80 KDM4E (0.59) KDM4EMAPTHSD17B10LMNATP53
SCHEMBL20547116 0.80 KDM4E (0.44) KDM4EMAPTHSD17B10LMNATP53
SCHEMBL824377 0.80 KDM4E (0.47) KDM4EMAPTHSD17B10LMNATP53
SCHEMBL19380361 0.79 KDM4E (0.44) KDM4EMAPTHSD17B10LMNATP53
SCHEMBL14868036 0.79 KDM4E (0.42) KDM4EMAPTHSD17B10LMNATP53
SCHEMBL18025278 0.79 KDM4E (0.42) KDM4EMAPTHSD17B10LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11696492-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-04 US disclosed
US-10978649-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-13 US disclosed
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-05 US disclosed
US-10749121-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-08-18 US disclosed
US-10403831-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 US disclosed
EP-2399922-B1 Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof UNIVERSAL DISPLAY CORP (US) 2019-06-26 EP disclosed
EP-1981898-B2 Metal complexes of imidazo[1,2-f]phenanthridine ligands for use in OLED devices UNIVERSAL DISPLAY CORP (US) 2019-04-10 EP disclosed
US-20190058138-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-02-21 US disclosed
US-20180130963-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-10 US disclosed
US-20180130963-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-10 US disclosed
US-20110073849-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f ]PHENANTHRIDINE AND DIIMIDAZO[1,2-a:1',2'-c ]QUNIAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF KNOWLES DAVID B 2011-03-31 US disclosed
US-20110073849-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f ]PHENANTHRIDINE AND DIIMIDAZO[1,2-a:1',2'-c ]QUNIAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF KNOWLES DAVID B 2011-03-31 US disclosed
US-7915415-B2 Metal complexes of cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1′,2′-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION (US) 2011-03-29 US disclosed
US-7915415-B2 Metal complexes of cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1′,2′-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION (US) 2011-03-29 US disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
WO-2007095118-A2 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f]PHENANTHRIDINE AND DIIMIDAZO[1,2-A:1',2'-C]QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORPORATION (US) 2007-08-23 WO disclosed
US-20070190359-A1 Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION 2007-08-16 US disclosed
US-20070190359-A1 Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110073849-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f ]PHENANTHRIDINE AND DIIMIDAZO[1,2-a:1',2'-c ]QUNIAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF NDUFC1, CD274, CRY1 KDM4E 3083/4885MAPT 2758/4885HSD17B10 4736/4885
US-20190058138-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIG1, L1CAM, LIG3 KDM4E 3788/4885MAPT 1900/4885HSD17B10 4692/4885
US-20180130963-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIG1, L1CAM, LIG3 KDM4E 3788/4885MAPT 1900/4885HSD17B10 4692/4885
US-10978649-B2 Organic electroluminescent materials and devices NR2C2, NR2E3, NCOA2 KDM4E 2578/4885MAPT 4645/4885HSD17B10 2130/4885
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C KDM4E 3612/4885MAPT 996/4885HSD17B10 4802/4885
US-11696492-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, ODC1 KDM4E 2142/4885MAPT 1097/4885HSD17B10 2357/4885
US-10749121-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 KDM4E 3788/4885MAPT 1900/4885HSD17B10 4692/4885
US-10403831-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 KDM4E 3788/4885MAPT 1900/4885HSD17B10 4692/4885
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR2C2, NR2E3, NCOA2 KDM4E 2578/4885MAPT 4645/4885HSD17B10 2130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.