Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 15/20 | 0.38 |
| ▸ | AGT | P01019 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16824592 | 0.88 | AGTR1 (0.37) | AGTR1AGTR2LTB4R2AGT | |
| SCHEMBL16824593 | 0.84 | AGTR1 (0.42) | AGTR1AGTR2AGT | |
| SCHEMBL21065260 | 0.82 | LTB4R2 (0.38) | AGTR1AGTR2LTB4R2AGT | |
| SCHEMBL16824598 | 0.81 | AGT (0.39) | AGTR1AGTR2LTB4R2AGT | |
| SCHEMBL21065276 | 0.80 | AGTR1 (0.34) | AGTR1AGTR2LTB4R2AGT | |
| SCHEMBL9709716 | 0.76 | AGT (0.41) | AGTR1AGTR2AGT | |
| SCHEMBL9709767 | 0.76 | AGT (0.39) | AGTR1AGTR2AGT | |
| SCHEMBL9709690 | 0.75 | AGTR1 (0.44) | AGTR1AGTR2LTB4R2AGT | |
| SCHEMBL9709627 | 0.75 | AGTR1 (0.38) | AGTR1AGTR2AGT | |
| SCHEMBL9709712 | 0.75 | AGT (0.41) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083582-B1 | A NEW PROCESS FOR THE PREPARATION OF CANDESARTAN CILEXETIL | FARMA GRS D O O (SI) | 2019-06-26 | — | — | EP | claimed |