SCHEMBL21065341

SCHEMBL21065341

CC(C)(NC(=O)c1ccc(-c2ccc(Cl)cc2)c(OCC2CC2)n1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 19/20 0.56
CNR1 P21554 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17142079 0.91 CNR2 (0.68) CNR2CNR1
SCHEMBL21117581 0.87 CNR2 (0.51) CNR2CNR1
SCHEMBL17142116 0.85 CNR2 (0.51) CNR2CNR1
SCHEMBL17142128 0.83 CNR1 (0.47) CNR2CNR1
SCHEMBL28441273 0.82 CNR2 (0.50) CNR2CNR1
SCHEMBL17142123 0.82 CNR2 (0.69) CNR2CNR1
SCHEMBL17142047 0.82 CNR2 (0.77) CNR2CNR1
SCHEMBL28897149 0.75 CNR2 (0.52) CNR2CNR1
SCHEMBL3250150 0.74 CNR2 (0.62) CNR2CNR1
SCHEMBL17142073 0.74 CNR2 (0.72) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3126349-B1 5,6-DISUBSTITUTED PYRIDINE-2-CARBOXAMIDES AS CANNABINOID RECEPTOR AGONISTS HOFFMANN LA ROCHE (CH) 2019-06-26 EP claimed