SCHEMBL21065347

SCHEMBL21065347

CC(C)CC(NC(=O)c1ccc(OCC2CC2)c(-c2ccc(Cl)cc2)n1)C(N)=O

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 19/20 0.61
CNR1 P21554 12/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17149760 1.00 CNR2 (0.61) CNR2CNR1
SCHEMBL17142105 0.87 CNR2 (0.58) CNR2CNR1
SCHEMBL17142104 0.78 CNR2 (0.56) CNR2CNR1
SCHEMBL411043 0.77 CNR2 (0.66) CNR2CNR1
SCHEMBL14226226 0.76 CNR2 (1.00) CNR2CNR1
SCHEMBL20057411 0.76 CNR2 (1.00) CNR2CNR1
SCHEMBL14226252 0.75 CNR2 (1.00) CNR2CNR1
SCHEMBL20057299 0.75 CNR2 (1.00) CNR2CNR1
SCHEMBL14226240 0.75 CNR2 (1.00) CNR2CNR1
SCHEMBL20057421 0.75 CNR2 (1.00) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3126349-B1 5,6-DISUBSTITUTED PYRIDINE-2-CARBOXAMIDES AS CANNABINOID RECEPTOR AGONISTS HOFFMANN LA ROCHE (CH) 2019-06-26 EP claimed
EP-3126349-B1 5,6-DISUBSTITUTED PYRIDINE-2-CARBOXAMIDES AS CANNABINOID RECEPTOR AGONISTS HOFFMANN LA ROCHE (CH) 2019-06-26 EP disclosed