SCHEMBL21065653

SCHEMBL21065653

NCC1(C(=O)C2CCCCC2)C=CC=CC1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.34
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21065655 0.85
SCHEMBL28182012 0.74
SCHEMBL28809595 0.73 HSD11B1 (0.38) HSD11B1CES2CES1
SCHEMBL4884855 0.62 HSD11B1 (0.33) HSD11B1
SCHEMBL7052648 0.62
SCHEMBL28247606 0.62 HSD11B1 (0.30) HSD11B1
SCHEMBL2479698 0.60 HSD11B1 (0.35) HSD11B1
SCHEMBL8519974 0.60 KMT2A (0.35)
SCHEMBL28209464 0.60 HSD11B1 (0.31) HSD11B1
SCHEMBL8941731 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3500553-A1 PROCESS FOR PRODUCING AN ISOCYANATE AND AT LEAST ONE FURTHER CHEMICAL PRODUCT IN AN INTEGRATED PRODUCTION Covestro Deutschland AG (DE) 2019-06-26 EP disclosed