Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 20/20 | 0.77 |
| ▸ | ESRRB | O95718 | 11/20 | 0.77 |
| ▸ | ESR1 | P03372 | 9/20 | 0.77 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.76 |
| ▸ | ESRRA | P11474 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20842108 | 0.88 | ESRRG (0.79) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL24354490 | 0.88 | ESRRG (0.79) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL21026585 | 0.81 | ESRRG (0.80) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842053 | 0.81 | ESRRG (1.00) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842168 | 0.80 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842215 | 0.79 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL30065746 | 0.74 | ESRRG (0.78) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842014 | 0.73 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842043 | 0.73 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20978480 | 0.73 | ESRRG (0.84) | ESRRGESRRBESR1KCNH2ESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190167820-A1 | NOVEL ARYL ETHENE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | HWANG SUNG YEOUN (KR) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190167820-A1 | NOVEL ARYL ETHENE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | ESRRG, ESR2, ESR1 | ESRRG 1/4885ESRRB 5/4885ESR1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.