Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 20/20 | 0.79 |
| ▸ | ESRRB | O95718 | 12/20 | 0.79 |
| ▸ | ESR1 | P03372 | 10/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.77 |
| ▸ | ESRRA | P11474 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20842108 | 1.00 | ESRRG (0.79) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL21026585 | 0.93 | ESRRG (0.80) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL21066214 | 0.88 | ESRRG (0.77) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842168 | 0.83 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842053 | 0.81 | ESRRG (1.00) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL24354541 | 0.81 | ESRRG (0.66) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842215 | 0.80 | ESRRG (0.98) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL20842039 | 0.79 | ESRRG (0.52) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL30065746 | 0.77 | ESRRG (0.78) | ESRRGESRRBESR1KCNH2ESRRA | |
| SCHEMBL21066254 | 0.76 | ESRRG (0.81) | ESRRGESRRBESR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3459936-B1 | NOVEL ARYL ETHANE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR) | 2022-04-27 | — | — | EP | disclosed |