SCHEMBL2106712

SCHEMBL2106712

CO/C=C(\C(=O)O)c1ccccc1Oc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.54
RAB9A P51151 1/20 0.50
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
NPSR1 Q6W5P4 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HTT P42858 2/20 0.45
LMNA P02545 3/20 0.45
GAA P10253 2/20 0.45
MAPT P10636 2/20 0.45
ALDH1A1 P00352 4/20 0.44
TSHR P16473 4/20 0.44
SCN1A P35498 1/20 0.44
SCN2A Q99250 1/20 0.44
SCN3A Q9NY46 1/20 0.44
TP53 P04637 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2847807 1.00 CTNNB1 (0.54) CTNNB1RAB9AKMT2AMEN1NPSR1
SCHEMBL2106717 1.00 CTNNB1 (0.54) CTNNB1RAB9AKMT2AMEN1NPSR1
SCHEMBL7163197 0.91 CTNNB1 (0.45) CTNNB1RAB9AKMT2AMEN1NPSR1
SCHEMBL2855935 0.89 KDM4E (0.57) CTNNB1RAB9AKMT2AMEN1HTT
SCHEMBL2107595 0.89 KDM4E (0.57) CTNNB1RAB9AKMT2AMEN1HTT
SCHEMBL2107591 0.89 KDM4E (0.57) CTNNB1RAB9AKMT2AMEN1HTT
SCHEMBL203716 0.88 CTNNB1 (0.51) CTNNB1RAB9AKMT2AMEN1NPSR1
SCHEMBL29358669 0.88 CTNNB1 (0.51) CTNNB1RAB9AKMT2AMEN1NPSR1
SCHEMBL6932850 0.88 CTNNB1 (0.51) CTNNB1RAB9AKMT2AMEN1NPSR1
SCHEMBL9152289 0.88 POLB (0.43) CTNNB1RAB9AKMT2AMEN1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3102570-A1 MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES Syngenta Participations AG (CH) 2016-12-14 EP disclosed
US-9314030-B2 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS INC. (US) 2016-04-19 US disclosed
WO-2015117563-A1 MICROBIOCIDAL HETEROBICYCLIC DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2015-08-13 WO disclosed
US-20150056258-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2015-02-26 US disclosed
US-8722198-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2014-05-13 US disclosed
US-20130164362-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2013-06-27 US disclosed
US-8158208-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2012-04-17 US disclosed
US-20090223408-A1 Use of Sub-Micron Copper Salt Particles in Wood Preservation PHIBROWOOD, LLC (US) 2009-09-10 US disclosed
US-20090123505-A1 Particulate Wood Preservative and Method for Producing Same PHIBROWOOD, LLC (US) 2009-05-14 US disclosed
EP-1830989-A2 USE OF SUB-MICRON COPPER SALT PARTICLES IN WOOD PRESERVATION Phibro-Tech, Inc. (US) 2007-09-12 EP disclosed
WO-2006065684-A2 USE OF SUB-MICRON COPPER SALT PARTICLES IN WOOD PRESERVATION PHIBRO-TECH, INC. (US) 2006-06-22 WO disclosed
WO-2006042128-A2 TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES PHIBRO-TECH, INC. (US) 2006-04-20 WO disclosed
US-20060062926-A1 Use of sub-micron copper salt particles in wood preservation KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC) 2006-03-23 US disclosed
US-20050252408-A1 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS NEW ZEALAND LIMITED (F/K/A OSMOSE NEW ZEALAND) (NZ) 2005-11-17 US disclosed
US-5925675-A N-sulfonyliminodithio compounds useful for in plant and material protection BAYER AKTIENGESELLSCHAFT (DE) 1999-07-20 US disclosed
US-5874025-A Timber preservative containing a copper compound BAYER AKTIENGESELLSCHAFT (DE) 1999-02-23 US disclosed
US-5767137-A FOR INDUSTRIAL MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1998-06-16 US disclosed
US-5703103-A MICROBIOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-30 US disclosed
US-5672617-A Medicaments containing 1-thiocarbamoyl-5-hydroxy-pyrazoles and their use as agents for combating septic shock BAYER AKTIENGESELLSCHAFT (DE) 1997-09-30 US disclosed