Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TCF4 | P15884 | 1/20 | 0.43 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203716 | 1.00 | CTNNB1 (0.51) | CTNNB1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL29358669 | 1.00 | CTNNB1 (0.51) | CTNNB1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL9150477 | 0.93 | RAB9A (0.46) | CTNNB1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL9150478 | 0.93 | RAB9A (0.46) | CTNNB1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL10390055 | 0.92 | POLB (0.48) | CTNNB1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL10390057 | 0.92 | POLB (0.48) | CTNNB1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL9152656 | 0.90 | MEN1 (0.44) | CTNNB1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL6933012 | 0.90 | MEN1 (0.44) | CTNNB1RAB9AKMT2AMEN1GAA | |
| SCHEMBL9152662 | 0.90 | MEN1 (0.44) | CTNNB1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL6933014 | 0.90 | MEN1 (0.44) | CTNNB1RAB9AKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0178826-B2 | Fungicides | SYNGENTA LTD (GB) | 2003-04-09 | — | — | EP | disclosed |
| EP-0546387-B1 | Substituted oximetheramides | BAYER AG (DE) | 1996-01-31 | — | — | EP | disclosed |
| US-5354779-A | Pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-11 | — | — | US | disclosed |
| EP-0546387-A1 | Substituted oximetheramides | BAYER AG (DE) | 1993-06-16 | — | — | EP | disclosed |
| EP-0178826-B1 | FUNGICIDES | ZENECA LIMITED (GB) | 1991-12-18 | — | — | EP | disclosed |
| EP-0307101-A3 | CHEMICAL PROCESS | ZENECA LIMITED (GB) | 1991-04-10 | — | — | EP | disclosed |
| EP-0307101-A2 | Chemical process | ZENECA LIMITED (GB) | 1989-03-15 | — | — | EP | disclosed |