Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.65 |
| ▸ | RAB9A | P51151 | 9/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3,5-Diphenylisoxazole SCHEMBL1421260 | 0.79 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL9438 | 0.79 | CYP1A2 (0.48) | RAB9AMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL8258186 | 0.77 | NPC1 (0.96) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL30636164 | 0.77 | CYP1A2 (0.47) | RAB9AMEN1KMT2ASMN1; SMN2CYP1A2 | |
| Phosphine SCHEMBL28114703 | 0.77 | CYP1A2 (0.47) | RAB9AMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL31519384 | 0.77 | CYP1A2 (0.47) | RAB9AMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL28309054 | 0.77 | CYP1A2 (0.47) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL842040 | 0.77 | CYP1A2 (0.47) | RAB9AMEN1KMT2ASMN1; SMN2CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL29843017 | 0.77 | CYP1A2 (0.47) | RAB9AMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL514705 | 0.77 | CYP1A2 (0.47) | RAB9AMEN1KMT2ASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |