SCHEMBL514705

SCHEMBL514705

[Ir].c1ccc(-c2cc[nH]n2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
IDO1 P14902 1/20 0.45
METAP2 P50579 1/20 0.45
KEAP1 Q14145 1/20 0.45
RAB9A P51151 2/20 0.43
POLB P06746 1/20 0.43
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
AKT1 P31749 1/20 0.41
AKT2 P31751 1/20 0.41
ALOX15 P16050 1/20 0.41
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
TSHR P16473 1/20 0.38
ATM Q13315 1/20 0.38
GAA P10253 1/20 0.37
ALDH1A1 P00352 2/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL842040 1.00 CYP1A2 (0.47) CYP1A2IDO1METAP2KEAP1RAB9A
SCHEMBL9438 0.98 CYP1A2 (0.48) CYP1A2IDO1METAP2KEAP1RAB9A
SCHEMBL30636164 0.95 CYP1A2 (0.47) CYP1A2IDO1METAP2KEAP1RAB9A
Phosphine SCHEMBL28114703 0.95 CYP1A2 (0.47) CYP1A2IDO1METAP2KEAP1RAB9A
SCHEMBL28309054 0.95 CYP1A2 (0.47) CYP1A2IDO1METAP2KEAP1RAB9A
SCHEMBL31519384 0.95 CYP1A2 (0.47) CYP1A2IDO1METAP2KEAP1RAB9A
Ammonia Solution, Strong SCHEMBL29843017 0.95 CYP1A2 (0.47) CYP1A2IDO1METAP2KEAP1RAB9A
SCHEMBL16800868 0.93 CYP1A2 (0.45) CYP1A2IDO1METAP2KEAP1RAB9A
Bicarbonate SCHEMBL7945138 0.89 TP53 (0.47) CYP1A2IDO1METAP2KEAP1RAB9A
Piperazine SCHEMBL28211307 0.87 CYP1A2 (0.41) CYP1A2IDO1METAP2KEAP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3846212-B1 PIXEL DEFINITION STRUCTURE, DISPLAY PANEL AND PREPARATION METHOD THEREFOR, AND DISPLAY APPARATUS BOE TECHNOLOGY GROUP CO LTD (CN) 2025-05-21 EP disclosed
CN-116606640-A Iridium metal organic compound covalent functionalized graphene oxide ternary nano hybrid material and preparation method thereof 江苏大学 2023-08-18 CN disclosed
CN-113851595-B Organic electroluminescent device and display device 京东方科技集团股份有限公司 2023-05-23 CN disclosed
CN-115295561-A Display panel, display device and manufacturing method 武汉天马微电子有限公司 2022-11-04 CN disclosed
CN-112002712-B Display panel, display device and manufacturing method 武汉天马微电子有限公司 2022-09-16 CN disclosed
CN-114730847-A Organic light emitting diode, method for preparing organic light emitting diode, display device and lighting device 京东方科技集团股份有限公司 2022-07-08 CN disclosed
CN-110875357-B Pixel defining structure, display panel, preparation method of display panel and display device 京东方科技集团股份有限公司 2022-05-24 CN disclosed
CN-113851595-A Organic electroluminescent device and display apparatus 京东方科技集团股份有限公司 2021-12-28 CN disclosed
US-20200388773-A1 Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir UNIV SOUTHERN CALIFORNIA (US) 2020-12-10 US disclosed
CN-112002712-A Display panel, display device and manufacturing method 武汉天马微电子有限公司 2020-11-27 CN disclosed
US-20080176102-A1 Organic light emitting devices; electroluminescent efficiency, durability; such as tris(1-(4-biphenyl)pyrazolato)iridium complexes THOMPSON MARK E 2008-07-24 US disclosed
CN-100387607-C Phenyl-pyrazole complexes of Ir UNIV SOUTHERN CALIFORNIA (US) 2008-05-14 CN disclosed
US-7338722-B2 Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2008-03-04 US disclosed
CN-1788012-A Phenyl-pyrazole complexes of Ir UNIV SOUTHERN CALIFORNIA (US) 2006-06-14 CN disclosed
US-20060024526-A1 tris(phenylpyrazole) iridium complex; stability THOMPSON MARK E 2006-02-02 US disclosed
EP-1606296-A2 PHENYL-PYRAZOLE COMPLEXES OF Ir UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2005-12-21 EP disclosed
US-6951694-B2 Organic light emitting devices with electron blocking layers THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2005-10-04 US disclosed
US-20040253478-A1 Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; UNIVERSITY OF SOUTHERN CALIFORNIA, THE 2004-12-16 US disclosed
WO-2004085450-A2 PHENYL-PYRAZOLE COMPLEXES OF IR THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2004-10-07 WO disclosed
US-20040048101-A1 Organic light emitting devices with electron blocking layers UNIVERSITY OF SOUTHERN CALIFORNIA, THE 2004-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040253478-A1 Iridium; phosphorescent, electroluminescent efficiencies in organic light emitting device; longer lifetimes, stability, efficiency in red, green and blue; one ligand has triplet energy corresponding to a wavelength 80 nm greater than wavelength corresponding to triplet energy of the other ligands; NR2E3, IK, NR2C2 CYP1A2 3478/4885IDO1 2261/4885METAP2 3447/4885
US-20200388773-A1 Phenyl and Fluorenyl Substituted Phenyl-Pyrazole Complexesof Ir EML4, RCOR3, CPNE4 CYP1A2 755/4885IDO1 2296/4885METAP2 3490/4885
US-20080176102-A1 Organic light emitting devices; electroluminescent efficiency, durability; such as tris(1-(4-biphenyl)pyrazolato)iridium complexes EML4, RNF4, LIG4 CYP1A2 1504/4885IDO1 2442/4885METAP2 4099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.