Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 18/20 | 0.82 |
| ▸ | AKT1 | P31749 | 1/20 | 0.74 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.74 |
| ▸ | GSK3A | P49840 | 1/20 | 0.74 |
| ▸ | GSK3B | P49841 | 1/20 | 0.74 |
| ▸ | STK4 | Q13043 | 1/20 | 0.74 |
| ▸ | STK3 | Q13188 | 1/20 | 0.74 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.74 |
| ▸ | STK26 | Q9P289 | 1/20 | 0.74 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.74 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15956798 | 0.88 | IGF1R (0.79) | IGF1RAKT1TGFBR1GSK3AGSK3B | |
| SCHEMBL15957070 | 0.85 | IGF1R (0.74) | IGF1RAKT1TGFBR1GSK3AGSK3B | |
| SCHEMBL1164728 | 0.85 | AKT1 (1.00) | IGF1RAKT1TGFBR1GSK3AGSK3B | |
| SCHEMBL12430931 | 0.85 | IGF1R (0.73) | IGF1RAKT1TGFBR1GSK3AGSK3B | |
| SCHEMBL22917504 | 0.83 | IGF1R (0.68) | IGF1RAKT1TGFBR1GSK3AGSK3B | |
| SCHEMBL15957087 | 0.81 | IGF1R (0.68) | IGF1RAKT1TGFBR1GSK3AGSK3B | |
| SCHEMBL28366859 | 0.80 | IGF1R (0.63) | IGF1RAKT1TGFBR1GSK3AGSK3B | |
| SCHEMBL12430680 | 0.79 | ULK1 (0.73) | IGF1RAKT1TGFBR1GSK3AGSK3B | |
| SCHEMBL30770809 | 0.79 | ULK1 (0.73) | IGF1RAKT1TGFBR1GSK3AGSK3B | |
| SCHEMBL22917408 | 0.79 | IGF1R (0.62) | IGF1RAKT1TGFBR1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |