Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.46 |
| ▸ | TYR | P14679 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29942328 | 1.00 | ALOX5 (0.46) | ALOX5TYRCYP3A4MAPTMEN1 | |
| SCHEMBL24868156 | 0.81 | NPC1 (0.42) | MAPTMEN1HTTKMT2ATDP1 | |
| SCHEMBL8980140 | 0.76 | NPC1 (0.44) | TDP1KDM4E | |
| SCHEMBL4879945 | 0.75 | ALOX5 (0.68) | ALOX5TYRCYP3A4MAPTMEN1 | |
| SCHEMBL2348704 | 0.75 | ALOX5 (0.68) | ALOX5TYRCYP3A4MAPTMEN1 | |
| SCHEMBL7516859 | 0.75 | ALOX5 (0.68) | ALOX5TYRCYP3A4MAPTMEN1 | |
| SCHEMBL8942889 | 0.75 | ALOX5 (0.68) | ALOX5TYRCYP3A4MAPTMEN1 | |
| SCHEMBL2344847 | 0.75 | ALOX5 (0.68) | ALOX5TYRCYP3A4MAPTMEN1 | |
| SCHEMBL8589296 | 0.75 | ALOX5 (0.68) | ALOX5TYRCYP3A4MAPTMEN1 | |
| SCHEMBL325823 | 0.75 | ALOX5 (0.68) | ALOX5TYRCYP3A4MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |