SCHEMBL21067516

SCHEMBL21067516

CN1CCC(C#N)(NC(=O)[C@H](CC2CCCCC2)NC(=O)N2CCOCC2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTSS P25774 20/20 1.00
CTSL P07711 4/20 1.00
CTSB P07858 2/20 0.53
CTSK P43235 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6106855 1.00 CTSS (1.00) CTSSCTSLCTSBCTSK
SCHEMBL6107169 0.94 CTSS (0.89) CTSSCTSL
SCHEMBL6108270 0.92 CTSS (0.86) CTSSCTSLCTSBCTSK
SCHEMBL6110300 0.92 CTSS (0.87) CTSSCTSLCTSB
SCHEMBL6107431 0.92 CTSS (0.85) CTSSCTSLCTSBCTSK
SCHEMBL14383643 0.92 CTSS (0.85) CTSSCTSLCTSBCTSK
SCHEMBL6106998 0.92 CTSS (0.94) CTSSCTSLCTSB
SCHEMBL6109403 0.91 CTSS (0.83) CTSSCTSL
SCHEMBL6105416 0.91 CTSS (0.84) CTSSCTSLCTSB
SCHEMBL5372410 0.91 CTSS (0.83) CTSSCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed