Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.96 |
| ▸ | POLA1 | P09884 | 1/20 | 0.96 |
| ▸ | POLD1 | P28340 | 1/20 | 0.96 |
| ▸ | TK1 | P04183 | 6/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | ALB | P02768 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.68 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.68 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zidovudine Triphosphate SCHEMBL23585776 | 0.98 | POLB (1.00) | POLBPOLA1POLD1TK1LMNA | |
| Zidovudine Triphosphate SCHEMBL19808965 | 0.98 | POLB (1.00) | POLBPOLA1POLD1TK1LMNA | |
| SCHEMBL18009254 | 0.93 | POLB (0.90) | POLBPOLA1POLD1TK1LMNA | |
| Azidothymidine Monophosphate SCHEMBL13450790 | 0.93 | POLB (0.83) | POLBPOLA1POLD1TK1LMNA | |
| Azidothymidine Monophosphate SCHEMBL14188505 | 0.93 | POLB (0.83) | POLBPOLA1POLD1TK1LMNA | |
| Azidothymidine Monophosphate SCHEMBL15094301 | 0.93 | POLB (0.83) | POLBPOLA1POLD1TK1LMNA | |
| SCHEMBL24705591 | 0.91 | POLB (0.87) | POLBPOLA1POLD1TK1LMNA | |
| SCHEMBL14370679 | 0.90 | POLB (0.80) | POLBPOLA1POLD1TK1LMNA | |
| SCHEMBL30272183 | 0.90 | POLB (0.79) | POLBPOLA1POLD1TK1LMNA | |
| SCHEMBL21473320 | 0.90 | POLB (0.79) | POLBPOLA1POLD1TK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3690055-B1 | METHOD FOR LABELLING CANCERIZATION-CAUSING CELL IN STEM CELLS | UNIV KAGOSHIMA (JP) | 2024-12-11 | — | — | EP | disclosed |
| EP-4356928-A1 | NUCLEOSIDE DIPHOSPHATE OR DIPHOSPHONATE PRODRUGS, OR NUCLEOSIDE ANALOGUE DIPHOSPHATE OR DIPHOSPHONATE PRODRUGS | Universität Hamburg (DE) | 2024-04-24 | — | — | EP | disclosed |
| US-20220357311-A1 | METHODS AND COMPOSITIONS FOR THE POSITIVE SELECTION OF PROTEIN DESTABILIZERS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-11-10 | — | — | US | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-11340216-B2 | Methods and compositions for the positive selection of protein destabilizers | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-05-24 | — | — | US | disclosed |
| CN-108776747-B | Method for estimating drug effect of zidovudine | 余鹏 | 2022-02-01 | — | — | CN | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |