SCHEMBL21067758

SCHEMBL21067758

NC(Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.61
DPP8 Q6V1X1 3/20 0.61
DPP9 Q86TI2 2/20 0.61
DPP7 Q9UHL4 2/20 0.61
FAP Q12884 1/20 0.61
ALDH1A1 P00352 2/20 0.60
CYP3A4 P08684 1/20 0.60
CYP2C9 P11712 1/20 0.60
PKM P14618 1/20 0.60
CYP2C19 P33261 1/20 0.60
F2 P00734 4/20 0.59
POLB P06746 1/20 0.57
FKBP1A P62942 1/20 0.56
NPC1 O15118 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21067756 1.00 DPP4 (0.61) DPP4DPP8DPP9DPP7FAP
SCHEMBL7102492 0.95 CYP3A4 (0.58) DPP4DPP8DPP9DPP7FAP
SCHEMBL7106999 0.95 CYP3A4 (0.58) DPP4DPP8DPP9DPP7FAP
SCHEMBL23752316 0.91 F2 (0.74) F2
SCHEMBL15077024 0.91 F2 (0.74) F2
SCHEMBL7148728 0.91 F2 (0.74) F2
SCHEMBL7101546 0.91 F2 (0.55) DPP4DPP8DPP9DPP7FAP
Hydrochloric Acid SCHEMBL7357933 0.90 F2 (0.73) F2
Hydrochloric Acid SCHEMBL7147479 0.90 F2 (0.73) F2
Hydrochloric Acid SCHEMBL7360853 0.90 DPP4 (0.61) DPP4DPP8DPP9DPP7FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed