SCHEMBL21067765

SCHEMBL21067765

O=C(Nc1cc(Cl)cc(Cl)c1)[C@H]1CC(=O)N(C2CCCCC2)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.70
SMN1; SMN2 Q16637 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5842594 0.78 ALDH1A1 (0.91) ALDH1A1SMN1; SMN2
SCHEMBL2246735 0.78 MEN1 (0.96) ALDH1A1SMN1; SMN2
SCHEMBL5843692 0.75 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2
SCHEMBL2185266 0.74 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2
SCHEMBL18154026 0.73 MEN1 (0.86) ALDH1A1SMN1; SMN2
SCHEMBL5842722 0.72 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2
SCHEMBL12728170 0.72 KMT2A (0.58) ALDH1A1SMN1; SMN2
SCHEMBL23177789 0.72 POLB (1.00) ALDH1A1SMN1; SMN2
SCHEMBL891915 0.72 POLB (1.00) ALDH1A1SMN1; SMN2
SCHEMBL5843614 0.72 POLB (1.00) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed