Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21067777 | 1.00 | POLB (0.36) | POLBNPC1RAB9ANPSR1TSHR | |
| SCHEMBL13628282 | 0.91 | NPC1 (0.36) | POLBNPC1RAB9ANPSR1TSHR | |
| SCHEMBL13628253 | 0.89 | NPC1 (0.37) | POLBNPC1RAB9ANPSR1TSHR | |
| SCHEMBL13628298 | 0.87 | RAB9A (0.36) | POLBNPC1RAB9ANPSR1TSHR | |
| SCHEMBL13628139 | 0.85 | NPC1 (0.37) | POLBNPC1RAB9ANPSR1TSHR | |
| SCHEMBL13628191 | 0.85 | NPC1 (0.39) | POLBNPC1RAB9ANPSR1TSHR | |
| SCHEMBL13628220 | 0.85 | MAPK8 (0.37) | POLBNPC1RAB9ANPSR1TSHR | |
| SCHEMBL13628138 | 0.85 | HCRTR1 (0.36) | POLBNPC1RAB9ANPSR1TSHR | |
| SCHEMBL13628280 | 0.85 | HCRTR1 (0.38) | POLBNPC1RAB9ANPSR1TSHR | |
| SCHEMBL13628244 | 0.85 | NPC1 (0.38) | POLBNPC1RAB9ANPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |