Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6518602 | 0.85 | AURKA (0.41) | CYP1A2CYP3A4CYP2C19ALDH1A1PLK1 | |
| SCHEMBL6514910 | 0.85 | CHEK1 (0.49) | CYP1A2ALDH1A1PLK1LMNAHTT | |
| SCHEMBL6508661 | 0.83 | TOP2A (0.53) | PLK1HTTKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL6515436 | 0.83 | CHEK1 (0.51) | ALDH1A1PLK1LMNAHPGDKDM4E | |
| SCHEMBL6523698 | 0.83 | TSHR (0.47) | ALDH1A1LMNAHPGDKDM4EPGR | |
| Hydrochloric Acid SCHEMBL6518743 | 0.82 | TOP2A (0.52) | HTTKDM4EMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL6521770 | 0.81 | HDAC3 (0.40) | ALDH1A1PLK1LMNAHPGDKDM4E | |
| SCHEMBL6508895 | 0.81 | MEN1 (0.35) | CYP1A2CYP3A4CYP2C19ALDH1A1PLK1 | |
| SCHEMBL6514357 | 0.80 | ALDH1A1 (0.44) | CYP1A2CYP3A4CYP2C19ALDH1A1LMNA | |
| SCHEMBL6522904 | 0.80 | GAA (0.51) | ALDH1A1LMNAMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |