Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 1.00 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 1.00 |
| ▸ | NAMPT | P43490 | 1/20 | 0.81 |
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310394 | 1.00 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1NAMPTGAAMAPK1 | |
| SCHEMBL2837762 | 0.86 | HSP90AA1 (0.75) | HSP90AA1HSP90AB1NAMPTGAAMAPK1 | |
| SCHEMBL13652557 | 0.85 | HSP90AA1 (0.73) | HSP90AA1HSP90AB1NAMPTGAAMAPK1 | |
| SCHEMBL1311373 | 0.85 | HSP90AA1 (0.73) | HSP90AA1HSP90AB1NAMPTGAAMAPK1 | |
| SCHEMBL1310766 | 0.81 | GAA (1.00) | HSP90AA1HSP90AB1NAMPTGAAMAPK1 | |
| SCHEMBL1310441 | 0.77 | HSP90AA1 (0.62) | HSP90AA1HSP90AB1NAMPTGAAMAPK1 | |
| SCHEMBL1309879 | 0.77 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1NAMPTGAAMAPK1 | |
| SCHEMBL10803827 | 0.75 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1NAMPTGAAMAPK1 | |
| SCHEMBL1310500 | 0.75 | KMT2A (0.60) | HSP90AA1HSP90AB1NAMPTGAAMAPK1 | |
| SCHEMBL8883066 | 0.72 | ALDH1A1 (0.57) | HSP90AA1HSP90AB1NAMPTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |