SCHEMBL2106911

SCHEMBL2106911

COC=C(C(=O)Oc1cccc(Oc2ncc(C)cn2)c1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
HTT P42858 2/20 0.38
MAPT P10636 2/20 0.38
GAA P10253 1/20 0.38
ALDH1A1 P00352 2/20 0.37
HPGDS O60760 3/20 0.36
CASP3 P42574 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
AKR1C3 P42330 1/20 0.35
PGR P06401 1/20 0.35
KDM4E B2RXH2 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8343387 0.90 KMT2A (0.44) KMT2AMEN1HTTMAPTGAA
SCHEMBL2106913 0.89 MEN1 (0.40) KMT2AMEN1HTTMAPTGAA
SCHEMBL2106908 0.89 MEN1 (0.40) KMT2AMEN1HTTMAPTGAA
SCHEMBL2856603 0.79 KDM4E (0.40) KMT2AMEN1HTTGAAALDH1A1
SCHEMBL2856612 0.79 KDM4E (0.40) KMT2AMEN1HTTGAAALDH1A1
SCHEMBL15848284 0.79 KDM4E (0.40) KMT2AMEN1HTTGAAALDH1A1
SCHEMBL2107654 0.79 MEN1 (0.57) KMT2AMEN1HTTMAPTGAA
SCHEMBL2107651 0.79 MEN1 (0.51) KMT2AMEN1HTTMAPTGAA
SCHEMBL2107655 0.79 MEN1 (0.51) KMT2AMEN1HTTMAPTGAA
SCHEMBL204614 0.78 GAA (0.39) GAAALDH1A1HPGDSKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9314030-B2 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS INC. (US) 2016-04-19 US disclosed
US-20150056258-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2015-02-26 US disclosed
US-8722198-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2014-05-13 US disclosed
US-20130164362-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2013-06-27 US disclosed
US-8158208-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2012-04-17 US disclosed
US-20090123505-A1 Particulate Wood Preservative and Method for Producing Same PHIBROWOOD, LLC (US) 2009-05-14 US disclosed
US-20050252408-A1 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS NEW ZEALAND LIMITED (F/K/A OSMOSE NEW ZEALAND) (NZ) 2005-11-17 US disclosed
US-5874025-A Timber preservative containing a copper compound BAYER AKTIENGESELLSCHAFT (DE) 1999-02-23 US disclosed