SCHEMBL2107654

SCHEMBL2107654

CC=C(C(=O)Oc1cccc(Oc2ncccn2)c1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
MAPT P10636 4/20 0.51
GAA P10253 2/20 0.51
HTT P42858 2/20 0.51
ALDH1A1 P00352 2/20 0.41
RAB9A P51151 2/20 0.40
NPC1 O15118 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
AKR1C3 P42330 1/20 0.40
LMNA P02545 3/20 0.40
TLR4 O00206 1/20 0.40
TLR2 O60603 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.39
PGR P06401 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8343387 0.89 KMT2A (0.44) MEN1KMT2AMAPTGAAHTT
SCHEMBL2108452 0.79 GCK (0.45) MEN1KMT2AALDH1A1RAB9ANPC1
SCHEMBL4454900 0.78 MEN1 (0.62) MEN1KMT2AMAPTGAAHTT
SCHEMBL8338935 0.78 AKR1C3 (0.44) AKR1C3TLR4TLR2PGR
SCHEMBL2107655 0.77 MEN1 (0.51) MEN1KMT2AMAPTGAAHTT
SCHEMBL2107651 0.77 MEN1 (0.51) MEN1KMT2AMAPTGAAHTT
SCHEMBL2857199 0.76 MEN1 (0.49) MEN1KMT2AMAPTGAAHTT
SCHEMBL2107666 0.76 KDM4E (0.62) MEN1KMT2AMAPTHTTALDH1A1
SCHEMBL4454902 0.75 MEN1 (0.54) MEN1KMT2AMAPTGAAHTT
SCHEMBL2108316 0.74 GPR17 (0.43) MEN1KMT2AMAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9314030-B2 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS INC. (US) 2016-04-19 US disclosed
US-20150056258-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2015-02-26 US disclosed
US-8722198-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2014-05-13 US disclosed
US-20130164362-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2013-06-27 US disclosed
US-8158208-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2012-04-17 US disclosed
US-20090123505-A1 Particulate Wood Preservative and Method for Producing Same PHIBROWOOD, LLC (US) 2009-05-14 US disclosed
WO-2006042128-A2 TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES PHIBRO-TECH, INC. (US) 2006-04-20 WO disclosed
US-20050252408-A1 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS NEW ZEALAND LIMITED (F/K/A OSMOSE NEW ZEALAND) (NZ) 2005-11-17 US disclosed
US-5925675-A N-sulfonyliminodithio compounds useful for in plant and material protection BAYER AKTIENGESELLSCHAFT (DE) 1999-07-20 US disclosed
US-5874025-A Timber preservative containing a copper compound BAYER AKTIENGESELLSCHAFT (DE) 1999-02-23 US disclosed
US-5703103-A MICROBIOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-30 US disclosed
US-5672617-A Medicaments containing 1-thiocarbamoyl-5-hydroxy-pyrazoles and their use as agents for combating septic shock BAYER AKTIENGESELLSCHAFT (DE) 1997-09-30 US disclosed