SCHEMBL2107178

SCHEMBL2107178

CO/C=C(\C(=O)OOc1cc(Oc2ccccc2F)ncn1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.35
RAF1 P04049 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.35
CHRM2 P08172 2/20 0.35
CHRM4 P08173 2/20 0.35
CHRM5 P08912 2/20 0.35
CHRM1 P11229 2/20 0.35
CHRM3 P20309 2/20 0.35
MAP4K4 O95819 1/20 0.34
MRGPRX1 Q96LB2 1/20 0.34
MAPT P10636 2/20 0.34
GCK P35557 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
PARP10 Q53GL7 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2107181 1.00 KDM4E (0.38) KDM4EMRGPRX4RAF1MEN1KMT2A
SCHEMBL4450542 0.91 CHRM4 (0.35) KDM4EMRGPRX4MEN1KMT2ALMNA
SCHEMBL4450551 0.91 CHRM4 (0.35) KDM4EMRGPRX4MEN1KMT2ALMNA
SCHEMBL8337937 0.89 SMN1; SMN2 (0.38) KDM4ERAF1MEN1KMT2ALMNA
SCHEMBL8337947 0.89 SMN1; SMN2 (0.38) KDM4ERAF1MEN1KMT2ALMNA
SCHEMBL8341499 0.86 L3MBTL1 (0.34) KDM4EMEN1KMT2ALMNAMAPT
SCHEMBL8499264 0.86 MAP4K4 (0.36) MAP4K4NPC1RAB9ASMN1; SMN2
SCHEMBL8341508 0.86 L3MBTL1 (0.34) KDM4EMEN1KMT2ALMNAMAPT
SCHEMBL2108063 0.86 MAP4K4 (0.36) MAP4K4NPC1RAB9ASMN1; SMN2
SCHEMBL30933024 0.82 SMN1; SMN2 (0.40) KDM4EMEN1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722198-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2014-05-13 US disclosed
US-20130164362-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2013-06-27 US disclosed
US-8158208-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2012-04-17 US disclosed
US-20090223408-A1 Use of Sub-Micron Copper Salt Particles in Wood Preservation PHIBROWOOD, LLC (US) 2009-09-10 US disclosed
US-20090123505-A1 Particulate Wood Preservative and Method for Producing Same PHIBROWOOD, LLC (US) 2009-05-14 US disclosed
EP-1830989-A2 USE OF SUB-MICRON COPPER SALT PARTICLES IN WOOD PRESERVATION Phibro-Tech, Inc. (US) 2007-09-12 EP disclosed
WO-2006065684-A2 USE OF SUB-MICRON COPPER SALT PARTICLES IN WOOD PRESERVATION PHIBRO-TECH, INC. (US) 2006-06-22 WO disclosed
US-20060062926-A1 Use of sub-micron copper salt particles in wood preservation KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC) 2006-03-23 US disclosed
US-20050252408-A1 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS NEW ZEALAND LIMITED (F/K/A OSMOSE NEW ZEALAND) (NZ) 2005-11-17 US disclosed
US-5925675-A N-sulfonyliminodithio compounds useful for in plant and material protection BAYER AKTIENGESELLSCHAFT (DE) 1999-07-20 US disclosed
US-5874025-A Timber preservative containing a copper compound BAYER AKTIENGESELLSCHAFT (DE) 1999-02-23 US disclosed
US-5767137-A FOR INDUSTRIAL MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1998-06-16 US disclosed
US-5703103-A MICROBIOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-30 US disclosed