Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 10/20 | 0.64 |
| ▸ | CYP51A1 | Q16850 | 11/20 | 0.60 |
| ▸ | PYGM | P11217 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606809 | 1.00 | PYGL (0.64) | PYGLCYP51A1PYGM | |
| SCHEMBL2107341 | 0.94 | PYGL (0.64) | PYGLCYP51A1PYGM | |
| SCHEMBL2606946 | 0.91 | CYP51A1 (0.61) | PYGLCYP51A1PYGM | |
| SCHEMBL2606771 | 0.91 | CYP51A1 (0.61) | PYGLCYP51A1PYGM | |
| SCHEMBL2108092 | 0.91 | CYP51A1 (0.61) | PYGLCYP51A1PYGM | |
| SCHEMBL2608592 | 0.90 | CYP51A1 (0.69) | PYGLCYP51A1PYGM | |
| SCHEMBL2109465 | 0.90 | CYP51A1 (0.69) | PYGLCYP51A1PYGM | |
| SCHEMBL2108107 | 0.90 | CYP51A1 (0.69) | PYGLCYP51A1PYGM | |
| SCHEMBL2108987 | 0.90 | PYGL (0.55) | PYGLCYP51A1 | |
| SCHEMBL13271638 | 0.90 | PYGL (0.55) | PYGLCYP51A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158622-B2 | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase | PROSIDION LIMITED (GB) | 2012-04-17 | — | — | US | disclosed |