Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 14/20 | 0.54 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.47 |
| ▸ | PYGM | P11217 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | IL2 | P60568 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2606838 | 1.00 | PYGL (0.54) | PYGLCYP51A1PYGMALBIL2 | |
| SCHEMBL2606884 | 0.91 | PYGL (0.66) | PYGLCYP51A1PYGMROCK2ROCK1 | |
| SCHEMBL2606968 | 0.88 | PYGL (0.51) | PYGLCYP51A1PYGMALBIL2 | |
| SCHEMBL2607058 | 0.88 | PYGL (0.54) | PYGLCYP51A1PYGMALBIL2 | |
| SCHEMBL2108843 | 0.87 | PYGL (0.51) | PYGLCYP51A1PYGMROCK2ROCK1 | |
| SCHEMBL2606974 | 0.87 | PYGL (0.51) | PYGLCYP51A1PYGMROCK2ROCK1 | |
| SCHEMBL2606819 | 0.85 | PYGL (0.52) | PYGLCYP51A1PYGMALBIL2 | |
| SCHEMBL2106634 | 0.85 | PYGL (0.59) | PYGLCYP51A1PYGMALBIL2 | |
| SCHEMBL2106631 | 0.85 | PYGL (0.59) | PYGLCYP51A1PYGMALBIL2 | |
| SCHEMBL2607056 | 0.85 | PYGL (0.51) | PYGLCYP51A1PYGMALBIL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158622-B2 | Pyrrolopyridine-2-carboxylic acid amide inhibitors of glycogen phosphorylase | PROSIDION LIMITED (GB) | 2012-04-17 | — | — | US | disclosed |