SCHEMBL21074253

SCHEMBL21074253

Cc1ccc2c(oc3ccccc32)c1N1c2ccccc2N(c2ccccc2)C1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
CYP2C19 P33261 1/20 0.33
PGR P06401 1/20 0.33
ALDH1A1 P00352 5/20 0.32
LMNA P02545 4/20 0.32
PPARG P37231 3/20 0.32
RXFP1 Q9HBX9 3/20 0.32
NR2E3 Q9Y5X4 3/20 0.32
NCOR2 Q9Y618 3/20 0.32
NPSR1 Q6W5P4 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
CA12 O43570 2/20 0.32
CA9 Q16790 2/20 0.32
TTR P02766 1/20 0.32
HTT P42858 3/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
MAPT P10636 2/20 0.31
TSHR P16473 2/20 0.31
HSD17B10 Q99714 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20349236 1.00 MEN1 (0.33) MEN1KMT2ACYP2C19PGRALDH1A1
SCHEMBL19999702 1.00 MEN1 (0.33) MEN1KMT2ACYP2C19PGRALDH1A1
SCHEMBL21074236 0.90 MEN1 (0.37) MEN1KMT2ACYP2C19PGRALDH1A1
SCHEMBL19999694 0.90 MEN1 (0.37) MEN1KMT2ACYP2C19PGRALDH1A1
SCHEMBL19999688 0.89 ALDH1A1 (0.33) MEN1KMT2ACYP2C19PGRALDH1A1
SCHEMBL21074237 0.89 ALDH1A1 (0.33) MEN1KMT2ACYP2C19PGRALDH1A1
SCHEMBL21074254 0.88 TSHR (0.33) MEN1KMT2AALDH1A1LMNANPSR1
SCHEMBL20349234 0.88 TSHR (0.33) MEN1KMT2AALDH1A1LMNANPSR1
SCHEMBL19999704 0.88 TSHR (0.33) MEN1KMT2AALDH1A1LMNANPSR1
SCHEMBL20349237 0.88 TSHR (0.33) MEN1KMT2AALDH1A1LMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3492480-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2021-10-20 EP disclosed
EP-3492480-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-06-05 EP disclosed