SCHEMBL21074296

SCHEMBL21074296

Cc1ccc2c(oc3ccccc32)c1N1c2ncccc2N(C(C)C)C1C

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
HSD17B10 Q99714 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
MAPK1 P28482 1/20 0.31
MEN1 O00255 1/20 0.31
NPY1R P25929 1/20 0.31
HTT P42858 1/20 0.31
NPY2R P49146 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
PPARG P37231 1/20 0.31
NCOA2 Q15596 1/20 0.31
NCOA1 Q15788 1/20 0.31
CYP1B1 Q16678 1/20 0.31
TLR7 Q9NYK1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16716695 1.00 TSHR (0.33) TSHRHSD17B10ALDH1A1MAPTMAPK1
SCHEMBL20349241 1.00 TSHR (0.33) TSHRHSD17B10ALDH1A1MAPTMAPK1
SCHEMBL21468819 0.92 TSHR (0.33) TSHRHSD17B10ALDH1A1MAPTMAPK1
SCHEMBL20349239 0.92 TSHR (0.33) TSHRHSD17B10ALDH1A1MAPTMAPK1
SCHEMBL16716728 0.92 TSHR (0.33) TSHRHSD17B10ALDH1A1MAPTMAPK1
SCHEMBL19999696 0.89 TSHR (0.34) TSHRHSD17B10ALDH1A1MAPTMAPK1
SCHEMBL21074289 0.89 TSHR (0.34) TSHRHSD17B10ALDH1A1MAPTMAPK1
SCHEMBL20349242 0.89 TSHR (0.34) TSHRHSD17B10ALDH1A1MAPTMAPK1
SCHEMBL16727571 0.89 TSHR (0.31) TSHRTLR7
SCHEMBL16716135 0.88 PIK3CA (0.32) CYP1A2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-11753427-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-12 US disclosed
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSITY DISPLAY CORPORATION (US) 2022-12-22 US disclosed
EP-3492480-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2021-10-20 EP disclosed
US-20210050532-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
US-20190319199-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-10-17 US disclosed
EP-3492480-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-06-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 TSHR 526/4885HSD17B10 3312/4885ALDH1A1 2211/4885
US-11753427-B2 Organic electroluminescent materials and devices OCIAD1, OSBP, OCIAD2 TSHR 3655/4885HSD17B10 581/4885ALDH1A1 259/4885
US-20210050532-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, LEF1 TSHR 3339/4885HSD17B10 3871/4885ALDH1A1 196/4885
US-20190319199-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, LARP7, L1CAM TSHR 879/4885HSD17B10 2110/4885ALDH1A1 881/4885
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP TSHR 3725/4885HSD17B10 1207/4885ALDH1A1 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.