Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035202 | 0.87 | HPGD (0.58) | HPGDMAPTKMT2AFGFR1ALDH1A1 | |
| SCHEMBL28979273 | 0.80 | GLA (0.59) | HPGDMAPTKMT2AMAPK1ALDH1A1 | |
| SCHEMBL30293257 | 0.80 | HPGD (0.50) | CA12CA1CA9HPGDHSD17B10 | |
| SCHEMBL6335098 | 0.79 | TP53 (0.46) | KCNJ1HSD17B10MAPTALDH1A1TP53 | |
| SCHEMBL10565741 | 0.78 | MAPT (0.58) | KCNJ1HPGDMAPTKMT2AMAPK1 | |
| SCHEMBL3499327 | 0.77 | CA12 (0.57) | CA12CA1CA9HPGDHSD17B10 | |
| SCHEMBL23768829 | 0.76 | KDM4E (0.44) | HPGDMAPTFGFR1ALDH1A1NPC1 | |
| SCHEMBL11809577 | 0.76 | OPRK1 (0.66) | HPGDMAPTKMT2AFGFR1MAPK1 | |
| SCHEMBL7287582 | 0.75 | CA12 (0.68) | CA12CA1CA9HPGDHSD17B10 | |
| SCHEMBL5213974 | 0.75 | HPGD (0.70) | CA12CA1CA9HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |