Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.67 |
| ▸ | HTR2A | P28223 | 14/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.67 |
| ▸ | HTR2C | P28335 | 6/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.67 |
| ▸ | HRH1 | P35367 | 6/20 | 0.67 |
| ▸ | DRD3 | P35462 | 4/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.67 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.67 |
| ▸ | DRD1 | P21728 | 2/20 | 0.67 |
| ▸ | DRD4 | P21917 | 2/20 | 0.67 |
| ▸ | DRD5 | P21918 | 2/20 | 0.67 |
| ▸ | HTR1D | P28221 | 2/20 | 0.67 |
| ▸ | HTR1B | P28222 | 2/20 | 0.67 |
| ▸ | HTR7 | P34969 | 2/20 | 0.67 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.67 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.67 |
| ▸ | HTR1A | P08908 | 6/20 | 0.59 |
| ▸ | HTR6 | P50406 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15486134 | 0.95 | DRD2 (0.65) | DRD2HTR2AKCNH2HTR2CADRA1A | |
| SCHEMBL15493491 | 0.95 | DRD2 (0.65) | DRD2HTR2AKCNH2HTR2CADRA1A | |
| SCHEMBL21074581 | 0.94 | DRD2 (0.64) | DRD2HTR2AKCNH2HTR2CADRA1A | |
| SCHEMBL15486018 | 0.94 | HTR2A (0.65) | DRD2HTR2AKCNH2HTR2CADRA1A | |
| SCHEMBL15489475 | 0.94 | HTR2A (0.63) | DRD2HTR2AKCNH2HTR2CADRA1A | |
| SCHEMBL21507375 | 0.93 | DRD2 (0.62) | DRD2HTR2AKCNH2HTR2CADRA1A | |
| SCHEMBL15485675 | 0.93 | DRD2 (0.62) | DRD2HTR2AKCNH2HTR2CADRA1A | |
| SCHEMBL15485630 | 0.92 | DRD2 (0.71) | DRD2HTR2AKCNH2HTR2CADRA1A | |
| SCHEMBL15493490 | 0.92 | DRD2 (0.71) | DRD2HTR2AKCNH2HTR2CADRA1A | |
| SCHEMBL15489439 | 0.92 | DRD2 (0.71) | DRD2HTR2AKCNH2HTR2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3556759-A1 | HAPTENS OF PALIPERIDONE | Janssen Pharmaceutica NV (BE) | 2019-10-23 | — | — | EP | disclosed |
| EP-2888258-B1 | HAPTENS OF PALIPERIDONE | JANSSEN PHARMACEUTICA NV (BE) | 2019-06-05 | — | — | EP | disclosed |