Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21783170 | 0.92 | KDM4E (0.43) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL21074773 | 0.89 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL21074742 | 0.89 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL23197067 | 0.88 | KCNH2 (0.43) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL21074736 | 0.86 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL7978646 | 0.84 | KCNH2 (0.51) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL7962322 | 0.84 | KCNH2 (0.51) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL7978642 | 0.84 | KCNH2 (0.51) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL7975716 | 0.82 | KCNH2 (0.50) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL7970259 | 0.81 | KCNH2 (0.49) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840549-B2 | Bisphosphonate quinolone conjugates and uses thereof | BIOVINC, LLC (US) | 2023-12-12 | — | — | US | disclosed |
| US-20210101920-A1 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-04-08 | — | — | US | disclosed |
| US-10865220-B2 | Bisphosphonate quinolone conjugates and uses thereof | BIOVINC, LLC (US) | 2020-12-15 | — | — | US | disclosed |
| US-20190169214-A1 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BIOVINC LLC (US) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10865220-B2 | Bisphosphonate quinolone conjugates and uses thereof | BPGM, PHPT1, NQO2 | KDM4E 3437/4885ALDH1A1 2346/4885HPGD 266/4885 |
| US-20190169214-A1 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BPGM, PHPT1, NQO2 | KDM4E 3437/4885ALDH1A1 2346/4885HPGD 266/4885 |
| US-11840549-B2 | Bisphosphonate quinolone conjugates and uses thereof | BPGM, PHPT1, NQO2 | KDM4E 3437/4885ALDH1A1 2346/4885HPGD 266/4885 |
| US-20210101920-A1 | BISPHOSPHONATE QUINOLONE CONJUGATES AND USES THEREOF | BPGM, PHPT1, NQO2 | KDM4E 3437/4885ALDH1A1 2346/4885HPGD 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.