Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | RORA | P35398 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15025837 | 0.96 | KDM4E (0.48) | KDM4EL3MBTL1ATMMAPTHTT | |
| SCHEMBL14407575 | 0.93 | KDM4E (0.52) | KDM4EL3MBTL1ATMMAPTHTT | |
| SCHEMBL14407596 | 0.93 | KDM4E (0.52) | KDM4EL3MBTL1ATMMAPTHTT | |
| SCHEMBL12154626 | 0.91 | KDM4E (0.58) | KDM4EL3MBTL1ATMMAPTHTT | |
| SCHEMBL21074933 | 0.91 | MAPT (0.39) | KDM4EMAPTHTTBCHEACHE | |
| SCHEMBL4402485 | 0.89 | KDM4E (0.57) | KDM4EL3MBTL1ATMMAPTHTT | |
| SCHEMBL13957097 | 0.89 | KDM4E (0.57) | KDM4EL3MBTL1ATMMAPTHTT | |
| SCHEMBL4251517 | 0.89 | KDM4E (0.57) | KDM4EL3MBTL1ATMMAPTHTT | |
| SCHEMBL12799780 | 0.88 | L3MBTL1 (0.52) | KDM4EL3MBTL1ATMMAPTHTT | |
| SCHEMBL17228088 | 0.88 | KDM4E (0.47) | KDM4EL3MBTL1ATMMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3493286-A1 | ORGANIC ELECTRONIC MATERIAL | Hitachi Chemical Company, Ltd. (JP) | 2019-06-05 | — | — | EP | disclosed |