Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 5/20 | 0.52 |
| ▸ | SCN7A | Q01118 | 4/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 17/20 | 0.51 |
| ▸ | SCN1A | P35498 | 2/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.45 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21075717 | 0.89 | SCN9A (0.49) | SCN5ASCN7ASCN9A | |
| SCHEMBL21075519 | 0.86 | SCN5A (0.49) | SCN5ASCN7ASCN9ASCN1ASCN2A | |
| SCHEMBL21075408 | 0.86 | SCN5A (0.49) | SCN5ASCN7ASCN9ASCN1ASCN2A | |
| SCHEMBL21075276 | 0.85 | SCN9A (0.53) | SCN5ASCN7ASCN9ASCN1ASCN2A | |
| SCHEMBL21075213 | 0.85 | SCN9A (0.53) | SCN5ASCN7ASCN9ASCN1ASCN2A | |
| SCHEMBL21075401 | 0.85 | SCN7A (0.68) | SCN5ASCN7ASCN9ASCN1ASCN2A | |
| SCHEMBL16758806 | 0.83 | SCN7A (0.75) | SCN5ASCN7ASCN9ASCN1ASCN2A | |
| SCHEMBL21075432 | 0.82 | SCN9A (0.50) | SCN5ASCN7ASCN9A | |
| SCHEMBL21075787 | 0.80 | SCN9A (0.46) | SCN5ASCN7ASCN9A | |
| SCHEMBL21075389 | 0.79 | SCN7A (0.68) | SCN5ASCN7ASCN9ASCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166939-B1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH INC (US) | 2019-06-05 | — | — | EP | disclosed |