Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 13/20 | 0.50 |
| ▸ | SCN7A | Q01118 | 6/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.45 |
| ▸ | SCN4A | P35499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21075787 | 0.91 | SCN9A (0.46) | SCN9ASCN7ASCN5A | |
| SCHEMBL17423087 | 0.88 | SCN9A (0.54) | SCN9ASCN7ASCN5ASCN4A | |
| SCHEMBL17428335 | 0.87 | SCN9A (0.63) | SCN9ASCN7ASCN5ASCN4A | |
| SCHEMBL17423056 | 0.87 | SCN9A (0.63) | SCN9ASCN7ASCN5ASCN4A | |
| SCHEMBL17428516 | 0.85 | SCN9A (0.53) | SCN9ASCN7ASCN5ASCN4A | |
| SCHEMBL17423234 | 0.84 | SCN9A (0.54) | SCN9ASCN7ASCN5ASCN4A | |
| SCHEMBL21075234 | 0.84 | SCN9A (0.61) | SCN9ASCN7ASCN5ASCN4A | |
| SCHEMBL18243750 | 0.83 | SCN9A (0.72) | SCN9ASCN7ASCN5ASCN4A | |
| SCHEMBL21075730 | 0.82 | SCN9A (0.48) | SCN9ASCN7ASCN5A | |
| SCHEMBL21075119 | 0.82 | SCN5A (0.52) | SCN9ASCN7ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166939-B1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH INC (US) | 2019-06-05 | — | — | EP | disclosed |