Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21075350 | 0.91 | SCN9A (0.44) | SCN9ASCN5A | |
| SCHEMBL17423255 | 0.91 | SCN9A (0.53) | SCN9ASCN5A | |
| SCHEMBL17423253 | 0.91 | SCN9A (0.53) | SCN9ASCN5A | |
| SCHEMBL21075630 | 0.90 | SCN9A (0.47) | SCN9ASCN5A | |
| SCHEMBL17428828 | 0.88 | SCN9A (0.47) | SCN9ASCN5A | |
| SCHEMBL19064949 | 0.87 | SCN9A (0.57) | SCN9ASCN5A | |
| SCHEMBL17428600 | 0.87 | SCN9A (0.57) | SCN9ASCN5A | |
| SCHEMBL20280368 | 0.87 | SCN9A (0.57) | SCN9ASCN5A | |
| SCHEMBL20697818 | 0.86 | SCN9A (0.41) | SCN9ASCN5A | |
| SCHEMBL21075107 | 0.85 | ROCK2 (0.46) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166939-B1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH INC (US) | 2019-06-05 | — | — | EP | disclosed |