Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.43 |
| ▸ | GYS1 | P13807 | 8/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17428303 | 0.83 | SCN9A (0.48) | SCN9ASCN7ASCN5A | |
| SCHEMBL17423024 | 0.83 | SCN9A (0.48) | SCN9ASCN7ASCN5A | |
| SCHEMBL19084009 | 0.82 | SCN9A (0.44) | SCN9AGYS1SCN7ASCN5A | |
| SCHEMBL19084006 | 0.82 | SCN9A (0.44) | SCN9AGYS1SCN7ASCN5A | |
| Trifluoroacetic Acid SCHEMBL19064935 | 0.81 | SCN9A (0.47) | SCN9ASCN7ASCN5A | |
| SCHEMBL17428435 | 0.81 | SCN9A (0.55) | SCN9AGYS1SCN7ASCN5AFFAR4 | |
| Trifluoroacetic Acid SCHEMBL17423118 | 0.81 | SCN9A (0.47) | SCN9ASCN7ASCN5A | |
| SCHEMBL17428454 | 0.81 | SCN9A (0.64) | SCN9AGYS1SCN7ASCN5A | |
| SCHEMBL17423164 | 0.81 | SCN9A (0.64) | SCN9AGYS1SCN7ASCN5A | |
| Trifluoroacetic Acid SCHEMBL19064795 | 0.80 | SCN9A (0.53) | SCN9AGYS1SCN7ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166939-B1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH INC (US) | 2019-06-05 | — | — | EP | disclosed |