Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 6/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22762580 | 0.81 | CTPS1 (0.49) | CTPS1 | |
| SCHEMBL22491626 | 0.79 | CTPS1 (0.55) | CTPS1 | |
| SCHEMBL21044263 | 0.79 | CTPS1 (0.55) | CTPS1 | |
| SCHEMBL22491734 | 0.79 | CTPS1 (0.55) | CTPS1 | |
| SCHEMBL22491710 | 0.79 | CTPS1 (0.51) | CTPS1 | |
| SCHEMBL21077234 | 0.78 | CTPS1 (0.40) | CTPS1NTRK1RAB9ALMNAMEN1 | |
| SCHEMBL22491634 | 0.75 | CTPS1 (0.63) | CTPS1 | |
| SCHEMBL22491743 | 0.75 | CTPS1 (0.63) | CTPS1 | |
| SCHEMBL22491633 | 0.75 | CTPS1 (0.63) | CTPS1 | |
| SCHEMBL22491665 | 0.73 | CTPS1 (0.51) | CTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |