Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 12/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTPS2 | Q9NRF8 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077112 | 0.92 | CTPS1 (0.56) | CTPS1PTGS2MEN1PSMD14KMT2A | |
| SCHEMBL21077068 | 0.90 | CTPS1 (0.52) | CTPS1PTGS2CTPS2 | |
| SCHEMBL21077048 | 0.90 | CTPS1 (0.43) | CTPS1PTGS2PIK3CGABL1 | |
| SCHEMBL21077158 | 0.88 | CTPS1 (0.60) | CTPS1PTGS2CTPS2 | |
| SCHEMBL21077115 | 0.88 | CTPS1 (0.46) | CTPS1ABL1GSK3BDYRK1A | |
| SCHEMBL21077253 | 0.86 | CTPS1 (0.58) | CTPS1ABL1MEN1PSMD14KMT2A | |
| SCHEMBL21076935 | 0.86 | CTPS1 (0.51) | CTPS1MEN1PSMD14KMT2ACTPS2 | |
| SCHEMBL21076917 | 0.85 | CTPS1 (0.59) | CTPS1CTPS2 | |
| SCHEMBL21044488 | 0.84 | CTPS1 (0.62) | CTPS1CTPS2 | |
| SCHEMBL30528780 | 0.84 | CTPS1 (0.62) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |