Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 13/20 | 0.58 |
| ▸ | CTPS2 | Q9NRF8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076917 | 0.88 | CTPS1 (0.59) | CTPS1CTPS2 | |
| SCHEMBL21076935 | 0.88 | CTPS1 (0.51) | CTPS1CTPS2MEN1KMT2APSMD14 | |
| SCHEMBL21076910 | 0.86 | CTPS1 (0.47) | CTPS1CTPS2MEN1KMT2APSMD14 | |
| SCHEMBL21077112 | 0.85 | CTPS1 (0.56) | CTPS1MEN1KMT2APSMD14 | |
| SCHEMBL31152525 | 0.84 | CTPS1 (0.76) | CTPS1CTPS2 | |
| SCHEMBL21044450 | 0.84 | CTPS1 (0.76) | CTPS1CTPS2 | |
| SCHEMBL21077068 | 0.83 | CTPS1 (0.52) | CTPS1CTPS2 | |
| SCHEMBL21077158 | 0.82 | CTPS1 (0.60) | CTPS1CTPS2 | |
| SCHEMBL21077048 | 0.78 | CTPS1 (0.43) | CTPS1ABL1 | |
| SCHEMBL21077199 | 0.77 | CTPS1 (0.53) | CTPS1CTPS2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |