Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 11/20 | 0.47 |
| ▸ | CTPS2 | Q9NRF8 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | STK17B | O94768 | 2/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.34 |
| ▸ | CFTR | P13569 | 2/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | DAPK2 | Q9UIK4 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077171 | 0.91 | CTPS1 (0.58) | CTPS1CTPS2 | |
| SCHEMBL21077074 | 0.89 | CTPS1 (0.60) | CTPS1CTPS2MAPK1PTGS2KDM4E | |
| SCHEMBL21077245 | 0.88 | CTPS1 (0.58) | CTPS1CTPS2IRAK4 | |
| SCHEMBL21077065 | 0.88 | CTPS1 (0.53) | CTPS1CTPS2 | |
| SCHEMBL21076941 | 0.86 | CTPS1 (0.50) | CTPS1CTPS2 | |
| SCHEMBL21077161 | 0.85 | CTPS1 (0.47) | CTPS1CTPS2 | |
| SCHEMBL21076891 | 0.85 | CTPS1 (0.57) | CTPS1CTPS2 | |
| SCHEMBL30528842 | 0.83 | CTPS1 (0.67) | CTPS1CTPS2 | |
| SCHEMBL21044244 | 0.83 | CTPS1 (0.67) | CTPS1CTPS2 | |
| SCHEMBL21077149 | 0.83 | CTPS1 (0.59) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |