Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 8/20 | 0.58 |
| ▸ | CTPS2 | Q9NRF8 | 2/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076890 | 0.92 | CTPS1 (0.57) | CTPS1CTPS2IRAK4ABCB1ABCC1 | |
| SCHEMBL21077134 | 0.91 | CTPS1 (0.58) | CTPS1CTPS2IRAK4NPC1RAB9A | |
| SCHEMBL21076938 | 0.88 | CTPS1 (0.47) | CTPS1CTPS2IRAK4 | |
| SCHEMBL21077074 | 0.87 | CTPS1 (0.60) | CTPS1CTPS2 | |
| SCHEMBL21077150 | 0.86 | CTPS1 (0.51) | CTPS1IRAK4NPC1RAB9AABCB1 | |
| SCHEMBL21077093 | 0.85 | CTPS1 (0.55) | CTPS1CTPS2ABCB1ABCC1 | |
| SCHEMBL21077207 | 0.84 | CTPS1 (0.69) | CTPS1CTPS2 | |
| SCHEMBL30528986 | 0.83 | CTPS1 (0.82) | CTPS1CTPS2 | |
| SCHEMBL21044118 | 0.83 | CTPS1 (0.82) | CTPS1CTPS2 | |
| SCHEMBL21077161 | 0.83 | CTPS1 (0.47) | CTPS1CTPS2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |