Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076995 | 0.79 | CTPS1 (0.41) | RAB9ANPC1POLBNPSR1 | |
| SCHEMBL14215419 | 0.76 | HDAC1 (0.36) | RAB9ANPC1HDAC1GAAALDH1A1 | |
| SCHEMBL21044072 | 0.76 | HDAC1 (0.39) | HDAC1GAAHRH3NPSR1 | |
| SCHEMBL32663074 | 0.73 | CTPS1 (0.43) | RAB9ANPC1POLBPDE5A | |
| SCHEMBL5516039 | 0.73 | TLR7 (0.36) | HDAC1GAASMN1; SMN2NPSR1 | |
| SCHEMBL22869169 | 0.70 | CTPS1 (0.40) | PDE5A | |
| SCHEMBL20640304 | 0.69 | MEN1 (0.50) | RAB9ANPC1POLBALDH1A1MAPT | |
| SCHEMBL22758529 | 0.65 | CTPS1 (0.37) | ALDH1A1 | |
| SCHEMBL22869122 | 0.65 | PDE5A (0.38) | HDAC1ALDH1A1PDE5AMAPTTP53 | |
| SCHEMBL21044111 | 0.64 | CTPS1 (0.44) | HDAC1PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |