Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22869122 | 0.87 | PDE5A (0.38) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL14215419 | 0.85 | HDAC1 (0.36) | HDAC1NPSR1GAAMEN1MAPK1 | |
| SCHEMBL5516039 | 0.81 | TLR7 (0.36) | HDAC1HDAC4NPSR1GAAMEN1 | |
| SCHEMBL5169008 | 0.78 | MEN1 (0.51) | NPSR1MEN1MAPK1KMT2A | |
| SCHEMBL20640304 | 0.77 | MEN1 (0.50) | MEN1MAPK1KMT2ABACE1 | |
| SCHEMBL27635825 | 0.76 | MEN1 (0.33) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL21076997 | 0.76 | RAB9A (0.34) | HDAC1NPSR1GAAHRH3 | |
| SCHEMBL21076995 | 0.74 | CTPS1 (0.41) | NPSR1 | |
| SCHEMBL22490785 | 0.74 | PDE5A (0.39) | HDAC1HDAC4HDAC3HDAC7HDAC2 | |
| SCHEMBL2588976 | 0.70 | LMNA (0.35) | HDAC4NPSR1GAAMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717459-B1 | COMPOUNDS | STEP PHARMA S A S (FR) | 2026-01-21 | — | — | EP | disclosed |
| US-12503466-B2 | Aminothiazole compounds as inhibitors of CTPS1 | STEP PHARMA S.A.S. (FR) | 2025-12-23 | — | — | US | disclosed |
| US-20240010645-A1 | Aminothiazole Compounds as Inhibitors of CTPS1 | STEP PHARMA S.A.S. (FR) | 2024-01-11 | — | — | US | disclosed |
| US-11655246-B2 | Aminothiazole compounds as inhibitors of CTPS1 | STEP PHARMA S.A.S. (FR) | 2023-05-23 | — | — | US | disclosed |
| US-20210002269-A1 | COMPOUNDS | STEP PHARMA S.A.S. (FR) | 2021-01-07 | — | — | US | disclosed |
| EP-3717459-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2020-10-07 | — | — | EP | disclosed |
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12503466-B2 | Aminothiazole compounds as inhibitors of CTPS1 | CTPS1, CTPS2, TBXAS1 | HDAC1 2381/4885HDAC4 3486/4885HDAC3 2940/4885 |
| US-11655246-B2 | Aminothiazole compounds as inhibitors of CTPS1 | CTPS1, CTPS2, TBXAS1 | HDAC1 2381/4885HDAC4 3486/4885HDAC3 2940/4885 |
| US-20210002269-A1 | COMPOUNDS | UGT1A1, CYP1A1, CYP19A1 | HDAC1 507/4885HDAC4 2460/4885HDAC3 715/4885 |
| US-20240010645-A1 | Aminothiazole Compounds as Inhibitors of CTPS1 | CTPS1, CTPS2, TBXAS1 | HDAC1 2381/4885HDAC4 3486/4885HDAC3 2940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.