Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 15/20 | 0.51 |
| ▸ | CTPS2 | Q9NRF8 | 4/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077149 | 0.93 | CTPS1 (0.59) | CTPS1CTPS2PIK3CGABL1 | |
| SCHEMBL21077161 | 0.89 | CTPS1 (0.47) | CTPS1CTPS2PIK3CGGSK3BDYRK1A | |
| SCHEMBL21076924 | 0.89 | CTPS1 (0.53) | CTPS1CTPS2 | |
| SCHEMBL21076932 | 0.86 | CTPS1 (0.52) | CTPS1CTPS2ABL1GSK3BDYRK1A | |
| SCHEMBL21077171 | 0.85 | CTPS1 (0.58) | CTPS1CTPS2 | |
| SCHEMBL21077159 | 0.85 | CTPS1 (0.49) | CTPS1CTPS2ABL1 | |
| SCHEMBL21077036 | 0.84 | CTPS1 (0.72) | CTPS1CTPS2 | |
| SCHEMBL21076891 | 0.84 | CTPS1 (0.57) | CTPS1CTPS2PIK3CG | |
| SCHEMBL21044134 | 0.83 | CTPS1 (0.73) | CTPS1CTPS2 | |
| SCHEMBL30528977 | 0.83 | CTPS1 (0.73) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |